San Francisco Giants at Los Angeles Dodgers odds, picks and predictions


The San Francisco Giants (14-8) open a 2-game road series against the Los Angeles Dodgers (14-7) Tuesday night. First pitch is at 10:10 p.m. ET at Dodger Stadium. Let’s analyze Tipico Sportsbook‘s lines around the Giants vs. Dodgers odds with MLB picks and predictions.

Season series: This is the first game of the season between the NL West Division rivals. The Giants won 10 of 19 regular-season games vs. L.A. in 2021, and including the postseason the teams split 24 games last year..

The Giants have lost 3 of their last 4 games and are coming off a home series loss to the Washington Nationals, losing 2 out of 3 to them, including Sunday’s 11-5 loss.

The Dodgers beat the Detroit Tigers 6-3 Sunday to clinch a 2-1 series win at home.

Giants at Dodgers projected starters

LHP Carlos Rodon vs. LHP Julio Urias

Rodon (3-0, 1.17 ERA) makes his 5th start. He has a 0.83 WHIP, 3.1 BB/9 and a league-leading 14.9 K/9 through 23 IP.

  • Has lasted at least 5 innings in every start and has not allowed more than 1 ER in any.
  • Has only 2 career starts against the Dodgers, going 0-1 with a 5.73 ERA against them.

Urias (1-1, 2.50 ERA) makes his 5th start. He has a 1.00 WHIP, 4.0 BB/9 and 7.5 K/9 in 18 IP.

  • Allowed 6 runs (3 earned) in 2 innings in his first start of the season, but has not allowed more than 1 run in a start since, posting a 0.56 ERA in his last 3.
  • Started 5 games last season against the Giants, going 2-1 with a 3.38 ERA in 29 1/3 IP.

Giants at Dodgers odds and lines

  • Money line (ML): Giants +115 (bet $100 to win $115) | Dodgers -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-200) | Dodgers -1.5 (+160)
  • Over/Under (O/U): 6.5 (O: -122 | U: -102)

Giants at Dodgers picks and predictions


Giants 3, Dodgers 2

Money line

These are 2 of the best teams in baseball with stud pitchers on the mound.

The Giants have been great on the road this season, starting off the year 8-3, while the Dodgers are 8-2 at home so far.

Both starters have been fantastic this season outside of Urias’ first start. Both teams’ bullpens have been great. The Giants have the third-lowest bullpen ERA in baseball at 2.59, while the Dodgers are right behind them at 2.77.

The Dodgers have not lost a series opener yet this season.

I give a slight edge to Rodon in this matchup, so I LEAN GIANTS (+115).

Run line/Against the spread

With 2 evenly matched teams, 2 great starters and 2 great bullpens, it is hard to think one team will pull away from the other.

The Dodgers have the best ATS record in the league at 14-7 ATS. The Giants are 12-10 ATS.

But as good as Rodon has been, I can’t expect the Dodgers to pull ahead and win by more than a run. And I actually lean toward a Giants win, but the line doesn’t make betting the Giants on the run line worth the money PASS. 


Rodon has not allowed more than 1 run in any start this season. Urias has not allowed more than 1 in his last 3 starts. Both bullpens have ERAs of under 3.00.

Everything about this matchup says that it will be low-scoring.

Take UNDER 6.5 (-102).

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Author: Lucy Green