2022 MLB All-Star Game odds, picks and prediction


The 2022 MLB All-Star Game takes place Tuesday at Dodger Stadium in Los Angeles with the FOX broadcast starting at 7:30 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the American League vs. National League odds with MLB picks and predictions.

The last time Chavez Ravine hosted the Midsummer Classic was 42 years ago in 1980 – the NL won 4-2.

The AL has won the last 8 All-Star Games, including 5-2 a year ago at Coors Field.

The NL’s last ASG win came in 2012 behind an 8-0 shutout at Kauffman Stadium in Kansas City. It was the last of 3 consecutive wins for the Senior Circuit.

The AL has won 20 of the past 24 All-Star Games – the 2002 contest ended in a 7-7 tie.

2022 All-Star Game projected starters

AL: LHP Shane McClanahan vs. NL: LHP Clayton Kershaw

The Rays’ McClanahan (10-3, 1.71 ERA) has a 0.80 WHIP, 1.5 BB/9 and 12.0 K/9 through 110 2/3 IP in 18 starts this season.

  • Leads majors in ERA and WHIP and his 147 K’s are tied for 2nd with Yankees RHP Gerrit Cole (RHP Dylan Cease of the White Sox has 150).
  • First All-Star appearance in just his 2nd year in majors.

The Dodgers’ Kershaw (7-2, 2.13 ERA) has a 0.91 WHIP, 1.5 BB/9 and 9.4 K/9 through 71 2/3 IP in 12 starts this season.

  • Will become 13th pitcher to start All-Star Game in his home park Max Scherzer was most recent in 2018 while with Nationals.
  • Eighth All-Star appearance in 15th MLB season – 1st since 2019.

2022 MLB All-Star Game starting lineups

National League
DH: S. Ohtani, LAA RF: R. Acuna Jr., ATL
RF: A. Judge, NYY CF: M. Betts, LAD
3B: R. Devers, BOS 3B: M. Machado, SD
1B: V. Guerrero Jr., TOR 1B: P. Goldschmidt, STL
LF: G. Stanton, NYY SS: T. Turner, LAD
CF: B. Buxton, MIN C: W. Contreras, CHC
SS: T. Anderson, CHW DH: W. Contreras, ATL
2B: A. Gimenez, CLE LF: J. Pederson, SF
C: A. Kirk, TOR 2B: J. McNeil, NYM

*-Angels OF Mike Trout, Astros 2B Jose Altuve, Phillies OF Bryce Harper and Marlins 2B Jazz Chisholm Jr. were voted in by the fans but are out due to injuries.

2022 MLB All-Star Game odds and lines

  • Money line (ML): American League -105 (bet $105 to win $100) | National League -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): AL -1.5 (+160) | NL +1.5 (-200)
  • Over/Under (O/U): 7.5 (O: -115 | U: -107)

MLB All-Star Game picks and predictions


AL 4, NL 2

Money line


There wasn’t much thought put into this coin-flip game since, as mentioned, the AL has dominated lately.

The AL’s run of winning 8 in a row and 20 of 24 is a trend hard to ignore.

Run line/Against the spread

BET 0.3 UNITS ON AL -1.5160).

Six of the victories during the AL’s current 8-game win streak have been by 2 or more runs.



I have loved playing Unders in these All-Star Games for years. There was no sweating last year’s “strongest play” of Under 11 (-115) with the AL coming out on top 5-2.

The Under is 12-2-1 in the past 15 All-Star Games.

Tuesday’s 5 p.m. PT start will benefit pitchers as the setting sun will make things tough for batters.

However, Tuesday’s O/U line is a seemingly low 7.5.

I still like it and I’m still suggesting it, but this isn’t a “strongest play” unless the line climbs to 9 – I don’t see that happening.

I am going to wait to make this play just in case the line climbs to 8.

Bonus wager


Currently, Tipico Sportsbook is not offering this line. If you can find it for -140 or less, play it.

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Author: Lucy Green